Advertisement

Picture EBD Group World of Partnering Opportunities 650x100px
Document › Details

Vividion Therapeutics, Inc.. (3/5/18). "Press Release: Vividion Therapeutics Announces Strategic Research Collaboration with Celgene Corporation to Discover Therapies Against Transformative, First-in-Class Targets". San Diego, CA.

Organisations Organisation Vividion Therapeutics Inc.
  Group Bayer (Group)
  Organisation 2 Celgene Corporation (Nasdaq: CELG)
  Group Bristol Myers Squibb (BMS) (Group)
Products Product small-molecule drug
  Product 2 drug discovery
Persons Person Vessey, Rupert (Celgene 201701 EVP + President RnD before Merck & Co 200906 VP Merck Research Laboratories)
  Person 2 Miralles, Diego (Flagship Pioneering 202102– CEO-Partner + CEO of Laronde before Vividion Tx +Adaptive Tx + JnJ)
     


Vividion to receive $101 million in upfront payment, including equity investment


Vividion Therapeutics, Inc., a biotechnology company using revolutionary proteomics and chemistry platforms, today announced a strategic research collaboration with Celgene Corporation. The multi-year collaboration is focused on the identification and development of unique small molecules against targets for a range of oncology, inflammatory and neurodegenerative indications. The collaboration is intended to advance new small molecules that function through the ubiquitin proteasome system, modulating specific protein levels for therapeutic benefit.

"Vividion has assembled a truly cutting-edge drug discovery platform that offers the opportunity to accelerate drug delivery in new and impactful ways by expanding the druggable proteome and addressing difficult targets," said Rupert Vessey, President, Research and Early Development, Celgene. "This collaboration will provide both companies with the opportunity for a comprehensive, accelerated drug discovery approach to develop first-in-class therapeutics in areas with high potential impact for patients."

"We are extremely pleased to collaborate with a leading medical innovator, Celgene. Our unique drug discovery capabilities provide new, expanded therapeutic possibilities," said Diego Miralles, CEO of Vividion. "We believe we can transform and accelerate the way small molecules are discovered, as our proprietary screening technology rapidly identifies and advances chemistry for targets that until now have remained undruggable."


Terms of the Collaboration

Vividion will receive an upfront payment of $101 million, which includes an equity investment from Celgene. The initial term of the collaboration is four years, with the opportunity for Celgene to extend for another two years for an additional payment.

The collaboration utilizes Vividion's platform to identify ligands and discover drug candidates against a selected list of high value, difficult-to-drug targets. This platform makes accessible the broad set of proteins expressed in human cells and for the first time allows protein-drug interactions to be assessed with precision directly in native biological systems.

Vividion will lead initial discovery efforts and identification of programs to be included in the collaboration, and Celgene will have the right to opt in on those programs at IND application acceptance. For certain programs, including the first program, Celgene will receive exclusive worldwide rights, with the potential for Vividion to receive up to double-digit royalties on sales and milestone payments. Other programs will allow for Celgene and Vividion to share equally either U.S. or worldwide development costs and commercialization profits and losses.


About Vividion Therapeutics

Vividion Therapeutics, Inc. is a biotechnology company focused on developing innovative therapeutics that treat major unmet clinical needs using the first platform for proteome-wide ligand and target discovery. The company's cutting-edge platform was spun out of the labs of Vividion's scientific founders, a team of experts in chemical biology and synthetic chemistry from The Scripps Research Institute in La Jolla, CA. Vividion is committed to advancing and applying its pioneering synthetic and proteomic chemistry platforms to create therapeutics that will make a transformative difference in patients. For more information, please visit www.vividion.com.


Media Contact:

Julie Rathbun
media@vividion.com
(858) 257-1535

   
Record changed: 2023-06-05

Advertisement

Picture Swiss Biotech Association Swiss Biotech Days 2024 SBD24 Basel 650x200px

More documents for Bayer (Group)


To subscribe to our free, monthly newsletter for the European life sciences, please send an e-mail to info@iito.de and simply fill the subject line with the word »LSE Newsletter«

Find more infos about advertising at [iito] web portals in our media flyer [iito] in a Nutshell [PDF file]

Advertisement

Picture EBD Group World of Partnering Opportunities 650x300px




» top